Scientist – Natural Products and Analytical Chemistry

Posted on January 3, 2017

Overview

Job Title

Scientist – Natural Products and Analytical Chemistry

Description

Edison Pharmaceuticals is building the world’s leading biological energy company focused on redox biochemistry. We are creating libraries of redox cofactors derived from natural sources for applications across the Life Sciences sector.

 

Position

We are seeking an experienced natural products/analytical chemist to help build screening libraries and to characterize active molecules from natural sources. This scientist will coordinate the screening of compounds and extracts targeting enzymes involved in biological energy metabolism.

Please note the Edison does not currently sponsor candidates or employees for employment or H1-B visas.  Only candidates legally documented to work in the US will be considered at this time.

Responsibilities
  • Create screening libraries of purified natural products and crude extracts;
  • Isolate bioactive natural products leads by bioassay-guided fractionation;
  • Elucidate structures of unknown molecules using spectroscopic and chemical methods;
  • Identify sources of additional chemical diversity around isolated lead structures;
  • Isolate compounds from microgram to multigram scale;
  • Format instrumentation and design work processes to achieve above responsibilities.
Reports To

VP, Chemical Biology

Qualifications

Essential Experience
  • Expertise in the isolation and analysis of small molecules. Experience in Metabolomics a plus.
  • Expertise in the separation of complex mixtures.
  • Strong chromatography, HPLC, LC-MS skills using a diverse array of LC bonded phases and MS detection
  • Expertise in the identification of unknowns.
  • Strong spectroscopy, MS, and NMR skills for structure determination of unknown organic molecules
  • Experience in designing work processes for the high throughput analysis of mixtures.
  • Experience with interfacing detectors and chromatography instrumentation.
  • Broad knowledge and understanding of molecular diversity from natural and synthetic sources.
  • Strong multitasking skills. Comfortable working in a highly dynamic environment.
  • Ability to work independently and in multidisciplinary teams.
  • PhD in natural products chemistry, organic chemistry, or analytical chemistry;
  • 5 years Life Sciences industry experience.

Personal

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